SOD1

gene

Also known as: superoxide dismutase 1

Learn about this topic in these articles:

In amyotrophic lateral sclerosis: Causes of ALS
TDP43, and SOD1.
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In Teepu Siddique: Research on ALS and other neurodegenerative disorders
… in a gene known as SOD1 (superoxide dismutase 1). SOD1 normally encodes an enzyme that neutralizes free radicals (potentially harmful by-products of cell metabolism). Siddique found, however, that its mutation resulted in the production of a defective version of the enzyme that led to the accumulation of free radicals in…
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