tau protein
biochemistry
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diagnosis of chronic traumatic encephalopathy
- In chronic traumatic encephalopathy: Neuropathology of CTE
…an abnormal protein known as tau. Tau-related abnormalities, which include aggregations and filaments known as neurofibrillary tangles, neuropil threads, and glial tangles, are most extensive around small cerebral vessels in the frontal and temporal lobes and are prominent in the basal ganglia, brainstem, and diencephalon. Similar microscopic neuropathologies are seen…
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role in Alzheimer disease
- In Alzheimer disease: Neuritic plaques and neurofibrillary tangles
…consist of a protein, called tau, that normally occurs in neurons. When incorrectly processed, tau molecules clump together and form tangles.
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