electrophilic aromatic substitution
chemistry
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aryl halides
- In organohalogen compound: Halogenation
…iron(III) halide (FeX3), brings about electrophilic aromatic substitution of one of the ring hydrogen atoms by the halogen.
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hydrocarbons
- In hydrocarbon: Reactions
…reaction of an arene is electrophilic aromatic substitution. Representative electrophilic aromatic substitutions, shown with benzene as the arene, include nitration, halogenation, sulfonation, alkylation, and acylation.
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phenols
- In phenol: Electrophilic aromatic substitution
Phenols are highly reactive toward electrophilic aromatic substitution, because the nonbonding electrons on oxygen stabilize the intermediate cation. This stabilization is most effective for attack at the ortho or para position of the ring; therefore, the hydroxyl group of a phenol is…
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