median lethal dose

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median lethal dose

pharmacology

Also known as: LD50, lethal dose 50

Learn about this topic in these articles:

drug action

In drug: Dose-response relationship
…result being expressed as the median lethal dose (LD₅₀), which is defined as the dose causing mortality in 50 percent of a group of animals.
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poisons and poisoning

In poison: Dose of exposure
…the lethal dose 50, or LD50. Toxicity ratings for chemicals are based on their LD50s. The toxicity rating indicates the amount of chemical required to produce death, but it should be remembered that all chemicals can kill. Thus, all chemicals are toxic. More important than the toxicity of a chemical…
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