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reverse transcriptase
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Following retrovirus infection, reverse transcriptase converts viral RNA into proviral DNA, which is then incorporated into the DNA of the host cell in the nucleus. cancer-causing retroviruses
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reverse transcriptase: References & Edit History

Additional Reading

Geoffrey M. Cooper, Rayla Greenberg Temin, and Bill Sugden (eds.), The DNA Provirus: Howard Temin’s Scientific Legacy (1995), details Temin’s research, his discovery of reverse transcriptase, and the influence and lasting impacts of his work. Neal Nathanson et al., Viral Pathogenesis and Immunity, 2nd ed. (2007), provides an introduction to the interactions between the immune system and infectious viruses. Gail Skowron and Richard Ogden (eds.), Reverse Transcriptase Inhibitors in HIV/AIDS Therapy (2006), is a detailed survey of the pharmacology and development of reverse transcriptase inhibitors.

Douglas Morier

Article Contributors

Primary Contributors

  • Douglas Morier
    Graduate student, University of California, Los Angeles.

Other Encyclopedia Britannica Contributors

Article History

Type Description Contributor Date
Add new Web site: BMC - BMC Bioinformatics - Modeling the functional state of the reverse transcriptase of hepatitis B virus and its application to probing drug-protein interaction. Nov 28, 2024
Add new Web site: Nature - The ISME Journal - Reverse transcriptase genes are highly abundant and transcriptionally active in marine plankton assemblages. Oct 03, 2024
Add new Web site: BMC - Retrovirology - When is it time for reverse transcription to start and go? Feb 02, 2024
Add new Web site: Journal of Biological Chemistry - Intrinsic properties of reverse transcriptase in reverse transcription. Nov 21, 2023
Add new Web site: Academia - Reverse Transcriptase Jumps and Gaps. Sep 14, 2023
Add new Web site: UNESCO-EOLSS - Reverse Transcriptase and cDNA Synthesis. Jul 31, 2023
Add new Web site: Biology LibreTexts - Reverse Transcription. Jun 08, 2023
Add new Web site: PNAS - A widespread class of reverse transcriptase-related cellular genes. Apr 10, 2023
Add new Web site: National Center for Biotechnology Information - Overview of Reverse Transcription. Jul 21, 2017
Add new Web site: Hypertexts For Biomedical Sciences - Reverse Transcriptase. Jul 27, 2012
New bibliography added. Mar 10, 2009
New article added. Mar 10, 2009
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