After Hamas took control of the Gaza Strip in 2007, Israel declared the Gaza Strip under Hamas a hostile entity and approved a series of sanctions that included power cuts, heavily restricted imports, and border closures. Hamas attacks on Israel continued, as did Israeli attacks on the Gaza Strip. After months of negotiations, in June 2008 Israel and Hamas agreed to implement a truce scheduled to last six months; however, the truce was threatened shortly thereafter as each accused the other of violations, which escalated in the last months of the agreement. On December 19 the truce officially expired amid accusations of violations on both sides. Broader hostilities erupted shortly thereafter as Israel, responding to sustained rocket fire, mounted a series of air strikes across the region—among the strongest in years—meant to target Hamas. After a week of air strikes, Israeli forces initiated a ground campaign into the Gaza Strip amid calls from the international community for a cease-fire. Following more than three weeks of hostilities—in which perhaps more than 1,000 were killed and tens of thousands were left homeless—Israel and Hamas each declared a unilateral cease-fire.

Beginning on November 14, 2012, Israel launched a series of air strikes in Gaza in response to an increase in the number of rockets fired from Gaza into Israeli territory over the previous nine months. The head of the ʿIzz al-Dīn al-Qassām Forces, Ahmed Said Khalil al-Jabari, was killed in the initial strike. Hamas retaliated with increasing rocket attacks on Israel, and hostilities continued until Israel and Hamas reached a cease-fire agreement on November 21.

In 2014 tensions between Israel and Hamas rose following the disappearance of three Israeli teenagers in the West Bank on June 12. Netanyahu accused Hamas of having abducted the youths, and he vowed not to let the crime go unpunished. Israeli security forces launched a massive sweep in the West Bank to search for the missing boys and to crack down on members of Hamas and other militant groups; several hundred Palestinians suspected of having militant ties were arrested, including several leaders of Hamas in the West Bank. On June 30 the boys were found dead in the West Bank, outside of Hebron.

In the Gaza Strip the atmosphere of heightened tension led to an increase in rocket attacks on Israel by the PIJ and other Palestinian militants. Those had been relatively infrequent since the 2012 cease-fire, but by late June 2014 rocket launches and Israeli reprisals had become a daily occurrence. On June 30, in response to these reprisals, Hamas fired its first rockets into Israel since the cease-fire. On July 8 Israel commenced a large-scale offensive in the Gaza Strip, using aerial bombing, missiles, and mortar fire to destroy a variety of targets that it claimed were associated with militant activity. After more than a week of bombardment failed to halt rocket fire from the Gaza Strip, Israeli forces launched a ground assault to destroy tunnels and other elements of the militants’ infrastructure. In early August Israeli leaders declared that the ground operation had fulfilled its mission, and Israeli troops and tanks pulled back from the Gaza Strip. Israeli air strikes continued, as did rocket and mortar attacks on Israel from the Gaza Strip.

After agreeing to several short-term cease-fires over the course of the conflict, Israeli and Palestinian leaders reached an open-ended cease-fire in late August. In exchange for the cessation of rocket fire from the Gaza Strip, Israel agreed to loosen restrictions on goods entering the Gaza Strip, expand the fishing zone off the coast, and reduce the size of the security buffer it enforced in areas adjacent to the Israeli border. Despite the high Palestinian death toll—estimated at more than 2,100—and widespread destruction in the Gaza Strip, Hamas leaders declared victory, trumpeting their ability to withstand Israeli attacks.

A series of border protests in Gaza in 2018, in which demonstrators attempted to cross the border into Israel and sent incendiary kites and balloons into Israel, was met with a violent response by Israel. The situation reached a peak on May 14, when about 40,000 people participated in the protests. Many of the protesters attempted to cross the border at once, and Israeli soldiers opened fire, killing about 60 people and wounding some 2,700 others. The violence continued to escalate, leading to Israeli air strikes and Hamas rocket fire into Israel. The fighting lasted several months and ended with a truce in November. Discussions for maintaining peace remained ongoing in the following years—even during periods of escalation—and led to the occasional easing of restrictions on the Gaza Strip.

In May 2021 tensions in Jerusalem boiled over and led to the greatest escalation of violence since 2014. After clashes between Israeli police and Palestinian protesters left hundreds injured, Hamas launched rockets into Jerusalem and southern and central Israel, prompting air strikes from Israel in response. After 11 days of fighting, Hamas and Israel reached a cease-fire.

In 2022, as Israel conducted incursions in the West Bank and the Gaza Strip to target militants, Hamas refrained from escalating confrontations in and around the Gaza Strip. Many observers, including members of the Israeli defense establishment, believed Hamas was focused on governing the Gaza Strip and was unprepared for a major confrontation. But on October 7, 2023, Hamas launched a coordinated land, sea, and air assault that took Israel by surprise. At least 1,200 Israelis were killed in the attacks—the deadliest day for Israel since its independence—and about 240 others were taken hostage.