epinephrine-stimulated cAMP synthesis
In cells the stimulatory effects of epinephrine are mediated through the activation of a second messenger known as cAMP (cyclic adenosine monophosphate). The activation of this molecule results in the stimulation of cell-signaling pathways that act to increase heart rate, to dilate blood vessels in skeletal muscle, and to break down glycogen to glucose in the liver.
epinephrine
hormone
Also known as: adrenaline
- Also called:
- adrenaline
- Related Topics:
- adrenal gland
- adrenochrome
- epinephrine autoinjector
- glycogenolysis
- norepinephrine
- On the Web:
- DermNet - The physiology and pharmacology of adrenaline (Dec. 10, 2024)
epinephrine, hormone that is secreted mainly by the medulla of the adrenal glands and that functions primarily to increase cardiac output and to raise glucose levels in the blood. Epinephrine typically is released during acute stress, and its stimulatory effects fortify and prepare an individual for either “fight or flight” (see fight-or-flight response). Epinephrine is closely related in structure to norepinephrine, differing only in the presence of a methyl group on the nitrogen side chain. In both substances, the amine (nitrogen-containing) group is attached to a catechol group (a benzene ring with two hydroxyl groups)—a structure unique to the catecholamines. ...(100 of 611 words)